Electrostatic Interactions between Peptides and the Molecular Chaperone DnaK
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چکیده
منابع مشابه
Electrostatic Interactions between Peptides and the Molecular Chaperone DnaK
The molecular chaperone DnaK prevents intracellular protein misfolding and aggregation by transiently binding with newly synthesized polypeptides and protein folding intermediates. DnaK preferentially binds to peptides with basic residues (Arg/Lys) present on the outside of a hydrophobic core. The electrostatic contribution toward DnaK/peptide binding was determined by measuring the dissociatio...
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Institute of Evolutionary Biology and Environmental Studies, University of Zurich, Zurich, 4 Switzerland 5 Swiss Institute of Bioinformatics, Lausanne, Switzerland 6 Department of Genetics, Smurfit Institute of Genetics, University of Dublin, Trinity College Dublin, 7 Dublin, Ireland 8 Instituto de Biología Molecular y Celular de Plantas (CSIC-UPV), Valencia, Spain 9 Department of Biology, Univ...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry B
سال: 2003
ISSN: 1520-6106,1520-5207
DOI: 10.1021/jp035872c